SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1A4Y_A_B
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- Mutation(s) in PDB:
KB40Q
- Mutation(s) cleaned: KB40Q
- Location: SUP
- Hold out type:
- Hold out protein(s): 1A4Y_A_B,1Z7X_W_X
- Affinity mutant: 9.3E-13
- Affinity wild-typen: 7.1E-16
- Reference: 2742853
- Protein 1: Ribonuclease inhibitor
- Protein 2: Angiogenin
- Method: SFFL
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 6.1E+07
- Kon wild-type (M-1s-1): 1.8E+08
- Koff mutatant (M-1s-1): 5.7E-05
- Koff wild-type (M-1s-1): 1.3E-07
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None