SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1A4Y_A_B
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- Mutation(s) in PDB:
YA434A,
DA435A
- Mutation(s) cleaned: YA434A,DA435A
- Location: COR,COR
- Hold out type:
- Hold out protein(s): 1A4Y_A_B,1Z7X_W_X
- Affinity mutant: 3.9E-11
- Affinity wild-typen: 3.9E-16
- Reference: 10413501
- Protein 1: Ribonuclease inhibitor
- Protein 2: Angiogenin
- Method: SFFL
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 7E+07
- Kon wild-type (M-1s-1): 2.8E+08
- Koff mutatant (M-1s-1): 2.7E-03
- Koff wild-type (M-1s-1): 1.1E-07
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None