SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1A22_A_B
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- Mutation(s) in PDB:
WB276A
- Mutation(s) cleaned: WB35A
- Location: COR
- Hold out type:
- Hold out protein(s): 1A22_A_B,1BP3_A_B
- Affinity mutant: 8.1E-10
- Affinity wild-typen: 3.4E-10
- Reference: 9571026
- Protein 1: Human growth hormone
- Protein 2: hGH binding protein
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 9.45E+04
- Kon wild-type (M-1s-1): 1.5E+05
- Koff mutatant (M-1s-1): 7.65E-05
- Koff wild-type (M-1s-1): 5.1E-05
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None