SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1A22_A_B
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- Mutation(s) in PDB:
SA57T,
TA60A,
SA62T,
NA63G,
RA64K,
EA65D,
TA67A,
KA70R,
NA72D,
LA73V
- Mutation(s) cleaned: SA57T,TA60A,SA62T,NA63G,RA64K,EA65D,TA67A,KA70R,NA72D,LA73V
- Location: SUR,INT,COR,COR,COR,RIM,SUP,SUR,INT,INT
- Hold out type:
- Hold out protein(s): 1A22_A_B,1BP3_A_B
- Affinity mutant: 5.8E-09
- Affinity wild-typen: 3.4E-10
- Reference: 2466339
- Protein 1: Human growth hormone
- Protein 2: hGH binding protein
- Method: RA
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None