SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1A22_A_B
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- Mutation(s) in PDB:
FA54H,
SA55T,
EA56S,
IA58L,
PA59A,
SA62E,
NA63D,
RA64K,
EA66Q,
TA67A,
KA70M,
SA71N,
NA72Q,
LA73K,
EA74D
- Mutation(s) cleaned: FA54H,SA55T,EA56S,IA58L,PA59A,SA62E,NA63D,RA64K,EA66Q,TA67A,KA70M,SA71N,NA72Q,LA73K,EA74D
- Location: INT,INT,RIM,INT,SUR,COR,COR,COR,SUR,SUP,SUR,SUR,INT,INT,SUR
- Hold out type:
- Hold out protein(s): 1A22_A_B,1BP3_A_B
- Affinity mutant: 2.3E-08
- Affinity wild-typen: 3.4E-10
- Reference: 2466339
- Protein 1: Human growth hormone
- Protein 2: hGH binding protein
- Method: RA
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None