SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3MZG_A_B
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- Mutation(s) in PDB:
HA180A
- Mutation(s) cleaned: HA167A
- Location: COR
- Hold out type:
- Hold out protein(s): 3MZG_A_B,3N06_A_B,3N0P_A_B,3NCB_A_B,3NCC_A_B,1BP3_A_B
- Affinity mutant: 1.32E-05
- Affinity wild-typen: 8.4E-06
- Reference: 20889499
- Protein 1: Prolactin
- Protein 2: Prolactin receptor
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 4E+04
- Kon wild-type (M-1s-1): 8E+03
- Koff mutatant (M-1s-1): 6E-01
- Koff wild-type (M-1s-1): 7E-02
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None