SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1JRH_LH_I
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- Mutation(s) in PDB:
NI48Q
- Mutation(s) cleaned: NI38Q
- Location: SUP
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 2.66E-08
- Affinity wild-typen: 1.44E-08
- Reference: 9878445
- Protein 1: mAbs A6
- Protein 2: Interferon gamma receptor
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 3.53E+05
- Kon wild-type (M-1s-1): 6.09E+05
- Koff mutatant (M-1s-1): 9.62E-03
- Koff wild-type (M-1s-1): 8.75E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None