SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1DAN_HL_UT
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- Mutation(s) in PDB:
RH134A
- Mutation(s) cleaned: RH125A
- Location: COR
- Hold out type:
- Hold out protein(s): 1DAN_HL_UT
- Affinity mutant: 1.31E-08
- Affinity wild-typen: 3.7E-09
- Reference: 8962059
- Protein 1: Factor VIIa
- Protein 2: Tissue factor
- Method: SPR
- Temperaute: 296 K
- Kon mutatant (M-1s-1): 1.4E+05
- Kon wild-type (M-1s-1): 1.6E+05
- Koff mutatant (M-1s-1): 1.8E-03
- Koff wild-type (M-1s-1): 5.7E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None