SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1TM1_E_I
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- Mutation(s) in PDB:
TI58D
- Mutation(s) cleaned: TI39D
- Location: COR
- Hold out type: Pr/PI
- Hold out protein(s): Pr/PI
- Affinity mutant: 2.42E-11
- Affinity wild-typen: 7E-13
- Reference: 7947796
- Protein 1: Subtilisin BPN
- Protein 2: Chymotrypsin inhibitor 2
- Method: IASP
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 1.4E+06
- Kon wild-type (M-1s-1): 5.5E+06
- Koff mutatant (M-1s-1): 3.4E-05
- Koff wild-type (M-1s-1): 3.9E-06
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None