SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2HLE_A_B
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- Mutation(s) in PDB:
LA95R
- Mutation(s) cleaned: LA87R
- Location: SUP
- Hold out type:
- Hold out protein(s): 2HLE_A_B,4L0P_A_B
- Affinity mutant: 1.9E-06
- Affinity wild-typen: 4E-08
- Reference: 16867992
- Protein 1: Ephrin type-B receptor 4
- Protein 2: Ephrin-B2
- Method: ITC
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): 5.2
- ΔH wild-type (kcal mol-1)): 3.3
- ΔS mutant (cal mol-1 K-1): 43.6
- ΔS wild-type (cal mol-1 K-1): 44.9