SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1PPF_E_I
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- Mutation(s) in PDB:
VI6I,
EI10D,
AI15V,
TI17S,
RI21M,
NI28S,
GI32S,
EI43D,
TI49I
- Mutation(s) cleaned: VI6I,EI10D,AI15V,TI17S,RI21M,NI28S,GI32S,EI43D,TI49I
- Location: SUR,SUR,COR,COR,RIM,SUR,COR,SUR,SUR
- Hold out type: Pr/PI
- Hold out protein(s): Pr/PI
- Affinity mutant: 4.55E-09
- Affinity wild-typen: 1.64E-10
- Reference: Stephen Ming-teh Lu, PhD Thesis, Purdue University, 2000
- Protein 1: Human leukocyte elastase
- Protein 2: Turkey ovomucoid third domain
- Method: FL
- Temperaute: 294 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None