SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1PPF_E_I
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- Mutation(s) in PDB:
EI10D,
RI21M,
KI29Q,
GI32S,
NI36S,
EI43D
- Mutation(s) cleaned: EI10D,RI21M,KI29Q,GI32S,NI36S,EI43D
- Location: SUR,RIM,RIM,COR,RIM,SUR
- Hold out type: Pr/PI
- Hold out protein(s): Pr/PI
- Affinity mutant: 7.69E-11
- Affinity wild-typen: 1.64E-10
- Reference: Stephen Ming-teh Lu, PhD Thesis, Purdue University, 2000
- Protein 1: Human leukocyte elastase
- Protein 2: Turkey ovomucoid third domain
- Method: FL
- Temperaute: 294 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None