SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1PPF_E_I
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- Mutation(s) in PDB:
EI10G,
LI18M,
YI20S,
LI23I,
KI29T,
GI32S,
HI52Y,
FI53P,
KI55V
- Mutation(s) cleaned: EI10G,LI18M,YI20S,LI23I,KI29T,GI32S,HI52Y,FI53P,KI55V
- Location: SUR,COR,COR,INT,RIM,COR,SUR,SUR,RIM
- Hold out type: Pr/PI
- Hold out protein(s): Pr/PI
- Affinity mutant: 2.17E-06
- Affinity wild-typen: 1.64E-10
- Reference: Stephen Ming-teh Lu, PhD Thesis, Purdue University, 2000
- Protein 1: Human leukocyte elastase
- Protein 2: Turkey ovomucoid third domain
- Method: FL
- Temperaute: 294 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None