SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
4WND_A_B
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- Mutation(s) in PDB:
RA221E,
NA283R
- Mutation(s) cleaned: RA201E,NA263R
- Location: SUP,COR
- Hold out type:
- Hold out protein(s): 4WND_A_B,3SF4_A_D,4G2V_A_B
- Affinity mutant: 3.9E-05
- Affinity wild-typen: 5.8E-08
- Reference: 22074847
- Protein 1: G-protein-signaling modulator 2 (LGN)
- Protein 2: FERM and PDZ domain-containing protein 4 (FRMPD4)
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None