2VLR_ABC_DE

• Mutation(s) in PDB: AE99S
• Mutation(s) cleaned: AE95S
• Location: SUP
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B
• Affinity mutant: 5.24E-06
• Affinity wild-typen: 5.24E-06
• Reference: 18275829
• Protein 1: HLA-A2 plus flu peptide
• Protein 2: JM22 TCR
• Method: ITC
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): -
• Kon wild-type (M^-1s^-1): -
• Koff mutatant (M^-1s^-1): -
• Koff wild-type (M^-1s^-1): -
• ΔH mutant (kcal mol^-1)): -23.0
• ΔH wild-type (kcal mol^-1)): -18.0
• ΔS mutant (cal mol^-1 K^-1): -50.3
• ΔS wild-type (cal mol^-1 K^-1): -33.5