2P5E_ABC_DE

• Mutation(s) in PDB: TD51Q, PD52S, WD53S, AE49G, IE50A, QE51G
• Mutation(s) cleaned: TD52Q,PD53S,WD54S,AE49G,IE50A,QE51G
• Location: SUP,INT,COR,COR,COR,RIM
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B,4N8V_G_ABC
• Affinity mutant: 8.15E-08
• Affinity wild-typen: 4.77E-11
• Reference: 17644531
• Protein 1: HLA-A2 plus NY-ESO peptide
• Protein 2: 1G4 TCR
• Method: SPR
• Temperaute: 298(assumed) K
• Kon mutatant (M^-1s^-1): 1.78E+04
• Kon wild-type (M^-1s^-1): 5.7E+05
• Koff mutatant (M^-1s^-1): 1.45E-03
• Koff wild-type (M^-1s^-1): 2.72E-05
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None