2PYE_ABC_DE

• Mutation(s) in PDB: QD51P, SD52F, SD53W, GE49S, AE50V, TE52M, LD95T, LD96S, DD97G, TD99S, LE94V
• Mutation(s) cleaned: QD52P,SD53F,SD54W,GE50S,AE51V,TE53M,LD96T,LD97S,DD98G,TD100S,LE95V
• Location: COR,RIM,RIM,SUP,RIM,COR,RIM,RIM,RIM,COR,COR
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B,4N8V_G_ABC
• Affinity mutant: 1.31E-09
• Affinity wild-typen: 8.15E-08
• Reference: 17644531
• Protein 1: HLA-A2 plus NY-ESO peptide
• Protein 2: 1G4 TCR
• Method: SPR
• Temperaute: 298(assumed) K
• Kon mutatant (M^-1s^-1): 1.81E+05
• Kon wild-type (M^-1s^-1): 1.78E+04
• Koff mutatant (M^-1s^-1): 2.37E-04
• Koff wild-type (M^-1s^-1): 1.45E-03
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None