2PYE_ABC_DE

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  • Mutation(s) in PDB: YD31D, TE52I, LD95T, LD96S, DD97G, TD99S, LE94V
  • Mutation(s) cleaned: YD32D,TE53I,LD96T,LD97S,DD98G,TD100S,LE95V
  • Location: COR,COR,RIM,RIM,RIM,COR,COR
  • Hold out type: TCR/pMHC
  • Hold out protein(s): TCR/pMHC,1JCK_A_B,4N8V_G_ABC
  • Affinity mutant: >2.4E-05
  • Affinity wild-typen: 8.15E-08
  • Reference: 17644531
  • Protein 1: HLA-A2 plus NY-ESO peptide
  • Protein 2: 1G4 TCR
  • Method: SPR
  • Temperaute: 298(assumed) K
  • Kon mutatant (M-1s-1): -
  • Kon wild-type (M-1s-1): -
  • Koff mutatant (M-1s-1): -
  • Koff wild-type (M-1s-1): -
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None