SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
5E9D_AB_CDE
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- Mutation(s) in PDB:
GD28E,
TD91Q,
VE50D,
AE99E
- Mutation(s) cleaned: GD27E,TD90Q,VE49D,AE98E
- Location: SUR,INT,SUR,RIM
- Hold out type: TCR/pMHC
- Hold out protein(s): TCR/pMHC,4N8V_G_ABC
- Affinity mutant: 1.6E-09
- Affinity wild-typen: 1.37E-07
- Reference: 27681597
- Protein 1: HLA-A2 plus MART-1 peptide
- Protein 2: RD1-MART1 TCR
- Method: FL
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None