1AO7_ABC_DE

• Mutation(s) in PDB: AE99M, GE100S, GE101A, RE102E
• Mutation(s) cleaned: AE96M,GE97S,GE98A,RE99E
• Location: RIM,COR,COR,RIM
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B
• Affinity mutant: 4.4E-09
• Affinity wild-typen: 3.2E-06
• Reference: 23805144
• Protein 1: HLA-A2 plus tax peptide
• Protein 2: A6 TCR
• Method: SPR
• Temperaute: 298(assumed) K
• Kon mutatant (M^-1s^-1): 5.5E+04
• Kon wild-type (M^-1s^-1): 2.3E+04
• Koff mutatant (M^-1s^-1): 2.2E-04
• Koff wild-type (M^-1s^-1): 7.4E-02
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None