3QFJ_ABC_DE

• Mutation(s) in PDB: FC5Y
• Mutation(s) cleaned: FC5Y
• Location: COR
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B
• Affinity mutant: 9E-07
• Affinity wild-typen: 1.2E-06
• Reference: 22019736
• Protein 1: HLA-A2 plus tax peptide
• Protein 2: A6 TCR
• Method: ITC
• Temperaute: 277 K
• Kon mutatant (M^-1s^-1): -
• Kon wild-type (M^-1s^-1): -
• Koff mutatant (M^-1s^-1): -
• Koff wild-type (M^-1s^-1): -
• ΔH mutant (kcal mol^-1)): 4.4
• ΔH wild-type (kcal mol^-1)): 5.9
• ΔS mutant (cal mol^-1 K^-1): 44.0
• ΔS wild-type (cal mol^-1 K^-1): 48.0