1LP9_ABC_EF

• Mutation(s) in PDB: KA66A
• Mutation(s) cleaned: KA66A
• Location: SUP
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B
• Affinity mutant: 7E-06
• Affinity wild-typen: 1E-06
• Reference: 17825839
• Protein 1: HLA-A2 plus P1049 peptide
• Protein 2: AHIII TCR
• Method: ITC
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): -
• Kon wild-type (M^-1s^-1): -
• Koff mutatant (M^-1s^-1): -
• Koff wild-type (M^-1s^-1): -
• ΔH mutant (kcal mol^-1)): -0.6
• ΔH wild-type (kcal mol^-1)): -3.9
• ΔS mutant (cal mol^-1 K^-1): 21.1
• ΔS wild-type (cal mol^-1 K^-1): 14.8