1AO7_ABC_DE

• Mutation(s) in PDB: EA63Q, KA66A
• Mutation(s) cleaned: EA63Q,KA66A
• Location: INT,SUP
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B
• Affinity mutant: 1.07E-05
• Affinity wild-typen: 2.23E-06
• Reference: 16197958
• Protein 1: HLA-A2 plus tax peptide
• Protein 2: A6 TCR
• Method: SPR
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): 3.4E+04
• Kon wild-type (M^-1s^-1): 4.9E+04
• Koff mutatant (M^-1s^-1): 3.6E-01
• Koff wild-type (M^-1s^-1): 1E-01
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None