1MI5_ABC_DE

• Mutation(s) in PDB: NE51A
• Mutation(s) cleaned: NE49A
• Location: COR
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B,4N8V_G_ABC
• Affinity mutant: 6.02E-06
• Affinity wild-typen: 1.25E-05
• Reference: 15640805
• Protein 1: HLA-B8 plus EB peptide
• Protein 2: LC13 TCR
• Method: SPR
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): 2.21E+04
• Kon wild-type (M^-1s^-1): 3.48E+04
• Koff mutatant (M^-1s^-1): 1.9E-01
• Koff wild-type (M^-1s^-1): 3.9E-01
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None