1AO7_ABC_DE

• Mutation(s) in PDB: KA66A
• Mutation(s) cleaned: KA66A
• Location: SUP
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B
• Affinity mutant: 1.87E-05
• Affinity wild-typen: 9.1E-07
• Reference: 11238586
• Protein 1: HLA-A2 plus tax peptide
• Protein 2: A6 TCR
• Method: SPR
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): 3.2E+03
• Kon wild-type (M^-1s^-1): 1.1E+05
• Koff mutatant (M^-1s^-1): 5E-02
• Koff wild-type (M^-1s^-1): 9.3E-02
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None