SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2BNR_ABC_DE
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- Mutation(s) in PDB:
VA67A
- Mutation(s) cleaned: VA67A
- Location: INT
- Hold out type: TCR/pMHC
- Hold out protein(s): TCR/pMHC,1JCK_A_B,4N8V_G_ABC
- Affinity mutant: 6.21E-06
- Affinity wild-typen: 3.2E-06
- Reference: 27734930
- Protein 1: HLA-A2 plus NY-ESO peptide
- Protein 2: 1G4 TCR
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 2.068966E+04
- Kon wild-type (M-1s-1): 2.4E+04
- Koff mutatant (M-1s-1): 1.68E-01
- Koff wild-type (M-1s-1): 1E-01
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None