SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3D5S_A_C
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- Mutation(s) in PDB:
AC41R
- Mutation(s) cleaned: AC31R
- Location: COR
- Hold out type:
- Hold out protein(s): 2GOX_A_B,3D5S_A_C,3D5R_A_C,2NOJ_A_B
- Affinity mutant: 2E-09
- Affinity wild-typen: 2.6E-08
- Reference: 18687868
- Protein 1: Complement C3d
- Protein 2: Fibrinogen-binding protein Efb-C
- Method: ITC
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -8.5
- ΔH wild-type (kcal mol-1)): -3.9
- ΔS mutant (cal mol-1 K-1): 11.4
- ΔS wild-type (cal mol-1 K-1): 21.5