3HG1_ABC_DE

• Mutation(s) in PDB: SE50Y, VE51G, GE52P, IE53Y
• Mutation(s) cleaned: SE50Y,VE51G,GE52P,IE53Y
• Location: INT,COR,SUP,RIM
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B
• Affinity mutant: 1.4E-06
• Affinity wild-typen: 2.6E-05
• Reference: 24196962
• Protein 1: HLA-A2 plus MART-1 peptide
• Protein 2: MEL5 TCR
• Method: SPR
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): -
• Kon wild-type (M^-1s^-1): -
• Koff mutatant (M^-1s^-1): -
• Koff wild-type (M^-1s^-1): -
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None