SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3HG1_ABC_DE
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- Mutation(s) in PDB:
SE50W,
VE51G,
GE52P,
IE53F,
GE99N,
TE100L,
EE102G,
LE103W
- Mutation(s) cleaned: SE50W,VE51G,GE52P,IE53F,GE99N,TE100L,EE102G,LE103W
- Location: INT,COR,SUP,RIM,COR,COR,SUR,INT
- Hold out type: TCR/pMHC
- Hold out protein(s): TCR/pMHC,1JCK_A_B
- Affinity mutant: 1.7E-07
- Affinity wild-typen: 2.6E-05
- Reference: 24196962
- Protein 1: HLA-A2 plus MART-1 peptide
- Protein 2: MEL5 TCR
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None