4MNQ_ABC_DE

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  • Mutation(s) in PDB: KC4A, IE50V, HE51G, PE52A, EE53G, YE54I
  • Mutation(s) cleaned: KC4A,IE49V,HE50G,PE51A,EE52G,YE53I
  • Location: COR,COR,COR,INT,SUR,COR
  • Hold out type: TCR/pMHC
  • Hold out protein(s): TCR/pMHC
  • Affinity mutant: 2.6E-06
  • Affinity wild-typen: 2E-09
  • Reference: 24196962
  • Protein 1: HLA-A2 plus telomerase peptide
  • Protein 2: ILA1 TCR
  • Method: SPR
  • Temperaute: 298 K
  • Kon mutatant (M-1s-1): 3.2E+03
  • Kon wild-type (M-1s-1): 8E+04
  • Koff mutatant (M-1s-1): 8.5E-03
  • Koff wild-type (M-1s-1): 1.6E-04
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None