SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
4MNQ_ABC_DE
Back
Reset view
- Mutation(s) in PDB:
KC4A,
IE50V,
HE51G,
PE52A,
EE53G,
YE54I
- Mutation(s) cleaned: KC4A,IE49V,HE50G,PE51A,EE52G,YE53I
- Location: COR,COR,COR,INT,SUR,COR
- Hold out type: TCR/pMHC
- Hold out protein(s): TCR/pMHC
- Affinity mutant: 2.6E-06
- Affinity wild-typen: 2E-09
- Reference: 24196962
- Protein 1: HLA-A2 plus telomerase peptide
- Protein 2: ILA1 TCR
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 3.2E+03
- Kon wild-type (M-1s-1): 8E+04
- Koff mutatant (M-1s-1): 8.5E-03
- Koff wild-type (M-1s-1): 1.6E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None