4MNQ_ABC_DE

• Mutation(s) in PDB: LC6A, HE51W, PE52E, EE53F, YE54E
• Mutation(s) cleaned: LC6A,HE50W,PE51E,EE52F,YE53E
• Location: COR,COR,INT,SUR,COR
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC
• Affinity mutant: 3.3E-06
• Affinity wild-typen: 2E-09
• Reference: 24196962
• Protein 1: HLA-A2 plus telomerase peptide
• Protein 2: ILA1 TCR
• Method: SPR
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): 1.5E+04
• Kon wild-type (M^-1s^-1): 8E+04
• Koff mutatant (M^-1s^-1): 4.9E-02
• Koff wild-type (M^-1s^-1): 1.6E-04
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None