1AO7_ABC_DE

• Mutation(s) in PDB: DD26W, RD27F, SD51M, SD100T, AE99M, GE100S, GE101A, RE102Q
• Mutation(s) cleaned: DD26W,RD27F,SD51M,SD94T,AE96M,GE97S,GE98A,RE99Q
• Location: COR,RIM,RIM,COR,RIM,COR,COR,RIM
• Hold out type: TCR/pMHC
• Hold out protein(s): TCR/pMHC,1JCK_A_B
• Affinity mutant: 6.2E-09
• Affinity wild-typen: 2.1E-06
• Reference: 20681514
• Protein 1: HLA-A2 plus tax peptide
• Protein 2: A6 TCR
• Method: SPR
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): 1.9E+04
• Kon wild-type (M^-1s^-1): 5.1E+04
• Koff mutatant (M^-1s^-1): 1.1E-04
• Koff wild-type (M^-1s^-1): 1.08E-01
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None