SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1YY9_CD_A
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- Mutation(s) in PDB:
SD53P
- Mutation(s) cleaned: SD53P
- Location: SUP
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 5.21E-09
- Affinity wild-typen: 1.31E-09
- Reference: 24380763
- Protein 1: Cetuximab fab
- Protein 2: Epidermal growth factor receptor
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 8.9E+05
- Kon wild-type (M-1s-1): 1.46E+06
- Koff mutatant (M-1s-1): 4.65E-03
- Koff wild-type (M-1s-1): 1.91E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None