1YY9_CD_A

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  • Mutation(s) in PDB: SD53P
  • Mutation(s) cleaned: SD53P
  • Location: SUP
  • Hold out type: AB/AG
  • Hold out protein(s): AB/AG
  • Affinity mutant: 5.21E-09
  • Affinity wild-typen: 1.31E-09
  • Reference: 24380763
  • Protein 1: Cetuximab fab
  • Protein 2: Epidermal growth factor receptor
  • Method: SPR
  • Temperaute: 298 K
  • Kon mutatant (M-1s-1): 8.9E+05
  • Kon wild-type (M-1s-1): 1.46E+06
  • Koff mutatant (M-1s-1): 4.65E-03
  • Koff wild-type (M-1s-1): 1.91E-03
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None