SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1FSS_A_B
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- Mutation(s) in PDB:
TB8V,
TB9N,
RB11K,
HB29R,
KB32R
- Mutation(s) cleaned: TB8V,TB9N,RB11K,HB29R,KB32R
- Location: COR,COR,RIM,RIM,RIM
- Hold out type:
- Hold out protein(s): 1FSS_A_B,1B41_A_B,1MAH_A_F
- Affinity mutant: 1.2E-09
- Affinity wild-typen: 3.1E-10
- Reference: 19643977
- Protein 1: T. californica acetylcholinesterase
- Protein 2: Fasciculin II
- Method: IASP
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 1.11E+08
- Kon wild-type (M-1s-1): 6.8E+07
- Koff mutatant (M-1s-1): 1.13E-01
- Koff wild-type (M-1s-1): 2.5E-02
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None