SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
4HRN_A_D
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- Mutation(s) in PDB:
SD51A
- Mutation(s) cleaned: SD43A
- Location: COR
- Hold out type:
- Hold out protein(s): 4HRN_A_D,3AAA_AB_C,2DVW_A_B
- Affinity mutant: 1.28E-08
- Affinity wild-typen: 3.3E-09
- Reference: 23527120
- Protein 1: Designed Ankyrin Repeat Protein H10-2-G
- Protein 2: erbB-2
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 2.85E+05
- Kon wild-type (M-1s-1): 3.22E+05
- Koff mutatant (M-1s-1): 3.5E-03
- Koff wild-type (M-1s-1): 1.07E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None