1N8Z_AB_C

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  • Mutation(s) in PDB: VC552A
  • Mutation(s) cleaned: VC536A
  • Location: SUR
  • Hold out type: AB/AG
  • Hold out protein(s): AB/AG
  • Affinity mutant: 1.33E-09
  • Affinity wild-typen: 1.31E-09
  • Reference: 23527120
  • Protein 1: Herceptin
  • Protein 2: erbB-2
  • Method: SPR
  • Temperaute: 298 K
  • Kon mutatant (M-1s-1): 9.6E+04
  • Kon wild-type (M-1s-1): 1.19E+05
  • Koff mutatant (M-1s-1): 1.28E-04
  • Koff wild-type (M-1s-1): 1.56E-04
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None