SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3R9A_AC_B
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- Mutation(s) in PDB:
AA328W
- Mutation(s) cleaned: AA323W
- Location: RIM
- Hold out type:
- Hold out protein(s): 3R9A_AC_B,2C0L_A_B
- Affinity mutant: 6.2E-06
- Affinity wild-typen: 3.5E-06
- Reference: 22529745
- Protein 1: Alanine-glyoxylate aminotransferase
- Protein 2: PEX5P
- Method: ITC
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): 6.31
- ΔH wild-type (kcal mol-1)): 3.8
- ΔS mutant (cal mol-1 K-1): 45.0
- ΔS wild-type (cal mol-1 K-1): 37.7