SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
4K71_A_BC
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- Mutation(s) in PDB:
MA418V,
AA420T,
GA505R
- Mutation(s) cleaned: MA416V,AA418T,GA503R
- Location: SUP,SUP,COR
- Hold out type:
- Hold out protein(s): 4K71_A_BC
- Affinity mutant: 4.5E-07
- Affinity wild-typen: 8E-09
- Reference: 24120761
- Protein 1: Human Serum Albumin
- Protein 2: FcRn
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 5.4E+03
- Kon wild-type (M-1s-1): 2.7E+04
- Koff mutatant (M-1s-1): 2.4E-03
- Koff wild-type (M-1s-1): 2.2E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None