SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3UII_A_P
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- Mutation(s) in PDB:
KA62A
- Mutation(s) cleaned: KA58A
- Location: RIM
- Hold out type:
- Hold out protein(s): 3UII_A_P,3UIG_A_P,3UIH_A_P
- Affinity mutant: 1.08E-05
- Affinity wild-typen: 1E-05
- Reference: 22244766
- Protein 1: Survivin
- Protein 2: Histone H3(1-10) peptide
- Method: ITC
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -7.71
- ΔH wild-type (kcal mol-1)): -5.51
- ΔS mutant (cal mol-1 K-1): -3.11
- ΔS wild-type (cal mol-1 K-1): 4.38