3UIH_A_P

• Mutation(s) in PDB: KA62Y, HA80W
• Mutation(s) cleaned: KA58Y,HA76W
• Location: RIM,COR
• Hold out type:
• Hold out protein(s): 3UIH_A_P,3UII_A_P,3UIG_A_P
• Affinity mutant: 1.98E-05
• Affinity wild-typen: 1.21E-04
• Reference: 22244766
• Protein 1: Survivin
• Protein 2: SmacN
• Method: ITC
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): -
• Kon wild-type (M^-1s^-1): -
• Koff mutatant (M^-1s^-1): -
• Koff wild-type (M^-1s^-1): -
• ΔH mutant (kcal mol^-1)): -4.44
• ΔH wild-type (kcal mol^-1)): -3.48
• ΔS mutant (cal mol^-1 K^-1): 6.64
• ΔS wild-type (cal mol^-1 K^-1): 6.24