SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3N85_A_LH
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- Mutation(s) in PDB:
SH32Y
- Mutation(s) cleaned: SH32Y
- Location: SUP
- Hold out type: AB/AG
- Hold out protein(s): AB/AG,3MZW_A_B
- Affinity mutant: 8.7E-10
- Affinity wild-typen: 7.9E-10
- Reference: 20654626
- Protein 1: HER2
- Protein 2: Fab37
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 1E+06
- Kon wild-type (M-1s-1): 1.3E+06
- Koff mutatant (M-1s-1): 8.8E-04
- Koff wild-type (M-1s-1): 9.8E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None