SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3M63_A_B
Back
Reset view
- Mutation(s) in PDB:
RA92A
- Mutation(s) cleaned: RA98A
- Location: RIM
- Hold out type:
- Hold out protein(s): 3M63_A_B,3M62_A_B,1S1Q_A_B,1XD3_A_B,2OOB_A_B
- Affinity mutant: 1.28E-07
- Affinity wild-typen: 1.75E-07
- Reference: 20427284
- Protein 1: Ubiquitin conjugation factor E4
- Protein 2: DSK2
- Method: ITC
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -7.8
- ΔH wild-type (kcal mol-1)): -10.1
- ΔS mutant (cal mol-1 K-1): 5.37
- ΔS wild-type (cal mol-1 K-1): -2.68