SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3L5X_A_HL
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- Mutation(s) in PDB:
NL92S,
EL93Y,
YL94G
- Mutation(s) cleaned: NL92S,EL93Y,YL94G
- Location: RIM,SUR,SUR
- Hold out type: AB/AG
- Hold out protein(s): AB/AG,3LB6_A_C
- Affinity mutant: 1.48E-10
- Affinity wild-typen: 7.54E-10
- Reference: 20226193
- Protein 1: Interleukin-13
- Protein 2: H2L6 fab
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 1.24E+06
- Kon wild-type (M-1s-1): 1.25E+06
- Koff mutatant (M-1s-1): 1.8E-04
- Koff wild-type (M-1s-1): 9.4E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None