SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
4UYP_A_D
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- Mutation(s) in PDB:
AD18F,
AD54F,
SD15I,
ID16N
- Mutation(s) cleaned: AD18F,AD54F,SD15I,ID16N
- Location: SUP,SUP,SUR,SUR
- Hold out type:
- Hold out protein(s): 4UYP_A_D,4UYQ_A_B,1OHZ_A_B,2CCL_A_B,5M2O_A_B
- Affinity mutant: 5.4E-08
- Affinity wild-typen: 2E-11
- Reference: 25855788
- Protein 1: A. cellulolyticus scaC cohesin
- Protein 2: A. cellulolyticus scaB dockerin
- Method: SPR
- Temperaute: 308 K
- Kon mutatant (M-1s-1): 1.2E+06
- Kon wild-type (M-1s-1): 2.1E+06
- Koff mutatant (M-1s-1): 6.7E-02
- Koff wild-type (M-1s-1): 4.2E-05
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None