SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2VN5_A_B
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- Mutation(s) in PDB:
SB47A,
TB48F,
TA45A,
NA47A,
YA49A
- Mutation(s) cleaned: SB42A,TB43F,TA35A,NA37A,YA39A
- Location: SUR,SUR,COR,SUP,COR
- Hold out type:
- Hold out protein(s): 2VN5_A_B
- Affinity mutant: 4.72E-07
- Affinity wild-typen: 1E-09
- Reference: 18445585
- Protein 1: C. cellulolyticum cipC cohesin
- Protein 2: C. cellulolyticum celCCA dockerin
- Method: ITC
- Temperaute: 308 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -14.6
- ΔH wild-type (kcal mol-1)): -20.8
- ΔS mutant (cal mol-1 K-1): -18.5
- ΔS wild-type (cal mol-1 K-1): -26.2