SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1BJ1_HL_VW
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- Mutation(s) in PDB:
ML4L,
TH28D,
NH31H,
HH101Y,
SH105T
- Mutation(s) cleaned: ML4L,TH28D,NH31H,HH101Y,SH105T
- Location: INT,SUR,COR,COR,RIM
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 1.1E-09
- Affinity wild-typen: 1.3E-08
- Reference: 10543973
- Protein 1: Fab-12
- Protein 2: VEGF
- Method: SPR
- Temperaute: 310 K
- Kon mutatant (M-1s-1): 5.4E+04
- Kon wild-type (M-1s-1): 5.1E+04
- Koff mutatant (M-1s-1): 5.9E-06
- Koff wild-type (M-1s-1): 6.6E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None