1CZ8_HL_VW

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  • Mutation(s) in PDB: LL4M, DH28T, HH31N, TH105S
  • Mutation(s) cleaned: LL4M,DH28T,HH31N,TH105S
  • Location: INT,SUR,COR,RIM
  • Hold out type: AB/AG
  • Hold out protein(s): AB/AG
  • Affinity mutant: 2E-10
  • Affinity wild-typen: <1.4E-10
  • Reference: 10543973
  • Protein 1: Fab-12
  • Protein 2: VEGF
  • Method: SPR
  • Temperaute: 298 K
  • Kon mutatant (M-1s-1): 2.5E+04
  • Kon wild-type (M-1s-1): 4.1E+04
  • Koff mutatant (M-1s-1): 4.5E-06
  • Koff wild-type (M-1s-1): 1.2E-04
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None