1MHP_HL_A

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  • Mutation(s) in PDB: TH50V, SL28Q, NL52Y
  • Mutation(s) cleaned: TH50V,SL27Q,NL51Y
  • Location: SUP,RIM,SUR
  • Hold out type: AB/AG
  • Hold out protein(s): AB/AG
  • Affinity mutant: 1.9E-09
  • Affinity wild-typen: 1.07E-08
  • Reference: 16597831
  • Protein 1: AQC2 fab
  • Protein 2: Integrin alpha-1
  • Method: SPR
  • Temperaute: 298(assumed) K
  • Kon mutatant (M-1s-1): 3.7E+05
  • Kon wild-type (M-1s-1): 2.5E+05
  • Koff mutatant (M-1s-1): 7E-04
  • Koff wild-type (M-1s-1): 2.6E-03
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None