SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1MHP_HL_A
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- Mutation(s) in PDB:
TH50V,
SL28Q,
NL52Y
- Mutation(s) cleaned: TH50V,SL27Q,NL51Y
- Location: SUP,RIM,SUR
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 1.9E-09
- Affinity wild-typen: 1.07E-08
- Reference: 16597831
- Protein 1: AQC2 fab
- Protein 2: Integrin alpha-1
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 3.7E+05
- Kon wild-type (M-1s-1): 2.5E+05
- Koff mutatant (M-1s-1): 7E-04
- Koff wild-type (M-1s-1): 2.6E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None