SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1YY9_CD_A
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- Mutation(s) in PDB:
SC26D,
TC31E,
NC93A,
ND56A,
TD61E
- Mutation(s) cleaned: SC26D,TC31E,NC93A,ND56A,TD61E
- Location: SUR,SUR,SUP,COR,SUR
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 1.63E-10
- Affinity wild-typen: 4.9E-10
- Reference: 17891135
- Protein 1: Cetuximab fab
- Protein 2: Epidermal growth factor receptor
- Method: FL
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None