SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1N8Z_AB_C
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- Mutation(s) in PDB:
HA91F
- Mutation(s) cleaned: HA91F
- Location: SUP
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 3.7E-10
- Affinity wild-typen: 3.5E-10
- Reference: 12206766
- Protein 1: Herceptin
- Protein 2: erbB-2
- Method: SPR
- Temperaute: 310 K
- Kon mutatant (M-1s-1): 9.7E+05
- Kon wild-type (M-1s-1): 1E+06
- Koff mutatant (M-1s-1): 3.6E-04
- Koff wild-type (M-1s-1): 3.5E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None