1N8Z_AB_C

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  • Mutation(s) in PDB: HA91F
  • Mutation(s) cleaned: HA91F
  • Location: SUP
  • Hold out type: AB/AG
  • Hold out protein(s): AB/AG
  • Affinity mutant: 3.7E-10
  • Affinity wild-typen: 3.5E-10
  • Reference: 12206766
  • Protein 1: Herceptin
  • Protein 2: erbB-2
  • Method: SPR
  • Temperaute: 310 K
  • Kon mutatant (M-1s-1): 9.7E+05
  • Kon wild-type (M-1s-1): 1E+06
  • Koff mutatant (M-1s-1): 3.6E-04
  • Koff wild-type (M-1s-1): 3.5E-04
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None